After installing Sphinx 1.10 on OSX Snow Leopard, I attempted to run the initial indexer and got the following error:
dyld: Library not loaded: libmysqlclient.16.dylib
Referenced from: /usr/local/bin/indexer
Reason: image not found
The fix was found after a little googling; just run this command:
sudo install_name_tool -change libmysqlclient.16.dylib /usr/local/mysql/lib/libmysqlclient.16.dylib /usr/local/bin/indexer
Take into account the location of your Sphinx install, but after this runs you should be all set.
I also just discovered that you’ll probably have to run the same command to get search working as well.